Cellophane (Cellulose Acetate) Tape Preparation

Cellophane (Cellulose Acetate) Tape Preparation is a method to collect the egg of pinworm, Enterobius vernicularis, as the female deposits the egg at night on the perianal folds.

Purpose:
To collect the egg of pinworm, Enterobius vernicularis, as the female deposits the egg at night on the perianal folds.

Principle:
Pinworm eggs will adhere to cellophane tape placed against the perianal folds. The tape is fixed to a microscope slide and examined microscopically.

Procedure:
  1.  Place the strip of cellophane tape around the end of a tongue depressor so that the sticky side is out by looping the tape around the top edge of the depressor.
  2.  Spread the buttocks and apply the tape to the perianal folds. Press tape firmly against the left and right perianal folds and anal opening.
  3. Remove the tape from the tongue depressor and place it sticky side down onto a microscope slide. Press firmly to remove all trapped air bubbles.
  4.  Lift one side of tape and apply one small drop of toluene or xylene to clear the tape. Press tape down onto slide.
  5.  Examine under low power (10x) with low light intensity. The entire area under the tape must be examined. Eggs are colorless and football shaped with one side flattened.
  6. Generally, specimens should be collected on five consecutive morning before a pinworm infection can be ruled out. The specimen is optimally collected before a bowel movement or bathing, since the eggs may otherwise not be detected.

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