This is a brief study guide in studying for Medical Laboratory Technologist (MLT) Hematology examination. This study companion guide has 24 cards and you can also refer to the table below this page.
MLT Hematology Examination Guide about Heme and Hemostasis
| Questions | Answers |
|---|---|
| The hemorrhagic problems assiciated with scurvy are due to a deficiency of ____________, which is a cofactor required for collagen synthesis. | Vitamin C |
| Approximately how many platelets dies an average megakaryocyte generate? | 2000 |
| Thrombocytopenia may be caused by all the following EXCEPT a. post-splenectomy b. chemotherapy c. decreased theombopoietin d. aplastic anemia | a. post-splenectomy |
| During the hemostatic process, platelets interacting with ans binding to other platelets is referred to as | aggregation |
| In platelet aggregation studies, certain aggregating agents induce a biphasic aggregation curve. To what is the second phase of aggregation directly related? | release of endogenous ADP |
| What is the operating principle of a platelet aggregometer? | change in optical density: as platelets aggregate, the optical density of the platelet-rich plasma decreases |
| What platelet aggregation agent characteristically yields a biphasic pattern when used in optimal concentration? | epinephrine |
| Which therapeutic agent affects platelet function? | aspirin |
| Apotent inhibitor of platelet aggregation released by endothelial cells is | prostacyclin |
| What is the approximate normal mean platelet volume (MPV) expressed in femtoliters (fL)? | 10 |
| The platelet parameter PCW refers to the | variation in cell size |
| What describes normal histograms showing platelet size distribution? | right-skewed, single peak |
| For the performance of manual platelet counts, what is the recommended type of microscopy? | phase |
| 20uL of blood are diluted in 1.98mL of diluent. This dilution is plated on both sides of a Neubauer-ruled counting chamber. 356 cells are seen when both large center squares are counted. What is the platelet count expressed as the number of cells/liter? | 178 X 10^9/L |
| What size threshold range does the electrical impedance method use to count particles as platelets? | 2-20fL |
| In storage pool diseases, platelets are primarily deficient in | ADP |
| What is the specimen of choice for routine coagulation testing? | 3.2% (1.109M) sodium citrate |
| The ratio of anticoagulant to blood for coagulation procedures should be 1 to | 9.0 |
| The liver is the site of synthesis of all the following EXCEPT a. Factor VIII b. Plasminogen c. Protein C d. von Willebrand's factor | d. von Willebrand's factor |
| When thrombin binds with thrombomodulin on the endothelial cell surface, thrombin can | activate protein C |
| What is the coagulation factor that has a sex-linked recessive inheritance pattern? | factor IX |
| What is associated with individuals having a Prekallikrein deficiency? | can have thrombotic complications |
| A soybean extract is used in specimen collection tubes for fibrin degradation product (FDP) tests to prevent | further fibrinogen degradation |
| The thrombin time will be prolonged in the presence of | factor II deficiency |
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